Abstract
Molecular analysis of West Nile virus (WNV) isolates obtained during a 2010 outbreak in Maricopa County, Arizona, USA, demonstrated co-circulation of 3 distinct genetic variants, including strains with novel envelope protein mutations. These results highlight the continuing evolution of WNV in North America and the current complexity of WNV dispersal and transmission.
Keywords:
Arizona; United States; West Nile virus; co-circulation; evolution; outbreak; phylogenetics; variants; viruses.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Arizona / epidemiology
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Biological Evolution
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Cluster Analysis
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Culex / virology*
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Disease Outbreaks*
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Genetic Variation
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Insect Vectors / virology*
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Phylogeny
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Viral Envelope Proteins / classification
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Viral Envelope Proteins / genetics*
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West Nile Fever / epidemiology*
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West Nile Fever / virology
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West Nile virus / classification
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West Nile virus / genetics*
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West Nile virus / isolation & purification